Naloxon-Nasenspray – Doppelpackung – jetzt auf Lager

What is naloxone nasal spray and how does it work?

Naloxone (brand name Narcan) is a competitive opioid receptor antagonist that rapidly displaces opioids from μ-opioid receptors, reversing opioid-induced respiratory depression, sedation, and hypotension. The 4 mg intranasal formulation is absorbed through the nasal mucosa with onset of action in 2–5 minutes, providing rapid reversal without injection. It has no effect in the absence of opioids.

Why does the twin pack include two doses?

A single 4 mg dose may not achieve reversal in overdoses involving potent synthetic opioids like fentanyl, carfentanil, or high-dose combinations. Current overdose response protocols recommend a second dose at 2–3 minutes if the patient does not respond to the first. The twin pack ensures both doses are immediately available without searching for a second device.

Who can administer naloxone nasal spray?

Naloxone nasal spray is designed for administration by bystanders, family members, law enforcement officers, firefighters, and first responders without clinical training. No injection skill is required — position the patient on their back, tilt the head back, insert the nozzle in one nostril, and press the plunger. All 50 U.S. states have standing order or access programs that allow naloxone dispensing without a prescription in some form.

What happens after naloxone is administered?

Most patients will begin to breathe more regularly within 2–5 minutes of intranasal administration. Because naloxone's duration of action (30–90 minutes) is typically shorter than the opioid causing the overdose, re-sedation can occur as the naloxone wears off. Every patient who receives naloxone should be transported to an emergency department regardless of initial response, and additional doses may be needed during transport.

Can the Naloxone Twin Pack be used with the MED-TAC Narcan Holster?

Yes. The MED-TAC Narcan Holster (NH-001) is specifically designed to hold two 4 mg naloxone nasal spray devices — exactly the twin-pack format. The holster provides quick-access belt carry with a heavy-duty snap closure, enabling rapid one-handed retrieval of both doses in an overdose emergency.