Axiostat Z-Fold Hemostatic Gauze – 100% Chitosan-Based Bleeding Control Solution

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SKU: MIL-300-Z
Type: Hemostatic Gauze
Vendor: Axiobio
PRODUCT INFORMATION

Axiostat Z-Fold Hemostatic Gauze – 100% Chitosan-Based Bleeding Control Solution

Stop bleeding faster with the only hemostatic gauze made entirely from Chitosan, not just coated with it.


Overview

The Axiostat Z-Fold Hemostatic Gauze is a revolutionary advancement in hemorrhage control. Unlike traditional gauze products infused with hemostatic agents, Axiostat is the only gauze on the market entirely made from Chitosan, a natural biopolymer derived from shellfish. This unique construction offers faster clotting, enhanced wound adhesion, and superior biocompatibility for use in both tactical and civilian trauma care.

Protonated Bioadhesive Technology (PBT®)

Axio Biosolutions employs the proprietary Protonated Bioadhesive Polymer technology (PBT®) to make its biopolymer-based hemostats, drug delivery systems and scaffolds with tailorable bioadhesive properties. These preparations are unique in a sense that they adhere to the tissues when needed and easily detach when their job is done.  This enables faster hemostasis due to the strong bioadhesion and electrostatic interaction between the positively charged chitosan and the negatively charged blood cells.

Whether you’re operating in a combat zone, first responder scene, or wilderness setting, Axiostat Z-Fold Gauze provides reliable, rapid control of moderate to severe bleeding in a compact, easy-to-apply format.


Key Features

  • 100% Chitosan-Based Fabric – Unlike other gauze that simply have Chitosan powder or particles sprayed on, Axiostat is manufactured entirely from Chitosan material, enhancing efficacy and durability.

  • Z-Fold Configuration – Designed for ease of packing deep or irregular wounds. Compact, tangle-free, and optimized for rapid deployment.

  • Highly Absorbent & Adhesive – Promotes immediate platelet activation and sticks to bleeding tissue, even in high-flow situations.

  • Biocompatible & Naturally Antimicrobial – Made from FDA-cleared Chitosan, offering broad-spectrum microbial resistance and safe for internal use.

  • Non-Heat Generating – Unlike kaolin-based gauze, Axiostat does not trigger exothermic reactions, making it safer for delicate tissue application.


Ideal For

  • Military medics & tactical operators
  • EMS & first responders
  • Law enforcement & SWAT teams
  • Wilderness medicine & expedition medics
  • Industrial & high-risk occupational settings
  • Individual first aid kits (IFAKs), trauma kits, and Stop the Bleed kits

Technical Specifications

  • Material: 100% Chitosan Hemostatic Fabric
  • Dimensions: Typically ~3” x 10 ft (folded length may vary)
  • Form Factor: Z-folded, vacuum-sealed pouch
  • Shelf Life: 3-5 years depending on storage
  • Certifications: CE Marked, FDA 510(k) Cleared
  • Storage: Lightweight, compact, and stable in extreme climates

How It Works

When applied to a wound, Axiostat’s Chitosan-based matrix interacts with blood components to accelerate clot formation. It adheres to wet tissues, forming a physical barrier and promoting natural coagulation—even in anticoagulated patients or those with hypothermia. Once bleeding is controlled, it can be removed without dislodging the clot.


Comparison vs. Standard Hemostatic Gauze

Feature Axiostat Z-Fold Other Hemostatic Gauze
Hemostatic Agent Base 100% Chitosan fabric Cotton gauze w/ Chitosan coating
Adhesion to Tissue High Low to moderate
Risk of Re-bleed After Removal Minimal Higher risk
Antimicrobial Properties Natural, broad-spectrum Varies by brand
Shelf Stability Excellent in field use Moderate

 

SPECS & MEASUREMENTS

Specifications coming soon. Contact us for detailed product information.

CLINICAL RATIONALE

Hemostatic Agents

1. Kaolin-Based Hemostatic Agents

(Examples: Combat Gauze, QuikClot EMS Rolled Gauze)

Clinical Rationale (Kaolin-Based):

Kaolin is an inorganic mineral hemostatic that accelerates the body’s natural clotting cascade by activating Factor XII (Hageman factor).
When applied to a bleeding wound, kaolin initiates the intrinsic coagulation pathway, resulting in rapid fibrin formation and stable clot development without generating heat.
Unlike older zeolite-based dressings, kaolin is completely non-exothermic, making it safe for extended wound packing and tissue contact.
It is a Committee on Tactical Combat Casualty Care (CoTCCC)–recommended dressing proven effective in both battlefield and civilian trauma care.

  • Triggers rapid clotting through Factor XII activation
  • No heat production — safe for direct tissue contact
  • Effective in hypothermic and coagulopathic patients
  • Durable gauze structure supports pressure dressings

2. Chitosan-Based Hemostatic Agents

(Examples: Celox Gauze, ChitoGauze, HemCon)

Clinical Rationale (Chitosan-Based):

Chitosan is a biopolymer derived from chitin, functioning through a positive-charge (cationic) mechanism that attracts negatively charged red blood cells and platelets.
This ionic reaction forms a gel-like clot that is independent of the body’s normal clotting factors, making it highly effective in patients with hypothermia or anticoagulant use.
Chitosan also has bacteriostatic properties that help reduce infection risk in contaminated wounds.
It is ideal for environments where traditional coagulation may be impaired.

  • Functions independently of natural clotting pathways
  • Effective in cold or anticoagulated patients
  • Forms an immediate mechanical seal on irregular wounds
  • Natural, biocompatible, and hypoallergenic

3. Cellulose-Based Hemostatic Agents (WoundClot)

(Examples: WoundClot Cellulose Gauze, WoundClot Battle Gauze)

Clinical Rationale (Cellulose-Based):

WoundClot represents a new generation of biosynthetic cellulose-based hemostats, engineered to form a hydrated, gelatinous matrix upon contact with blood.
This matrix absorbs fluid, stabilizes clot formation, and provides a scaffold for platelet and fibrin bonding.
Unlike other agents, WoundClot maintains its structure for hours, supporting sustained hemostasis under arterial or high-pressure bleeding.
It is completely bio-absorbable and non-allergenic, dissolving naturally within 5–7 days without removal.

  • Rapid gel-matrix formation supports durable clot structure
  • Fully bio-absorbable — no removal required
  • Effective for arterial, venous, and mixed bleeding
  • Allergy-safe, non-animal, and non-mineral composition

Clinical Summary

All hemostatic technologies—Kaolin, Chitosan, and Cellulose—share the goal of rapid external hemorrhage control, the leading preventable cause of trauma death.
Each mechanism is suited to specific medical and operational environments:

  • Kaolin: Dependable, non-exothermic, CoTCCC-recommended standard for general tactical use.
  • Chitosan: Ideal for anticoagulated, cold, or maritime conditions.
  • Cellulose (WoundClot): Advanced, bio-absorbable option for high-pressure or surgical-transition wounds.

Selection should be based on environment, casualty physiology, and evacuation timeline. Each mechanism offers unique advantages that complement modern tactical and civilian trauma protocols.

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$38.95
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