Axiostat Z-Fold Hemostatic Gauze – 100% Chitosan-Based Bleeding Control Solution

Key Specifications

Product Overview

Axiostat MIL-300-Z brings the same 100% chitosan PBT® muco-adhesive technology as the L88 patch into a Z-fold gauze configuration optimized for deep wound packing. At 7.6 cm × 300 cm (approximately 3 in. × 10 ft.), it provides the full-length gauze format required for deep penetrating wounds, wound tunnels, and junctional hemorrhage sites where a surface patch cannot reach the bleeding source. The Z-fold configuration reduces the packaged footprint (160 × 140 × 10 mm) for IFAK and combat vest carry while preserving rapid deployment capabilities.

The PBT® mechanism is charge-based: protonated chitosan carries a strong positive charge that binds electrostatically to the negatively charged membranes of red blood cells and wound tissue. This creates a rapid, firm muco-adhesive bond that physically seals the bleeding site — forming a mechanical barrier to blood flow within one minute of application with constant pressure. The mechanism is independent of the coagulation cascade, making it effective in hypothermic patients, those on anticoagulants, and patients with coagulopathy. The gauze is flexible, allowing it to be packed into deep wounds with complex geometries, reaching bleeding surfaces that are inaccessible to surface patches. Absorbency is at least 15 times its weight in blood, with moisture content not exceeding 35%.

Axiostat MIL-300 (the non-Z-fold rolled version) and MIL-300-Z share the same chemistry and NSN codification. The Z-fold packaging specifically reduces the packaged cube size for individual operator carry compared to the rolled format. Axiostat products are deployed by military and special forces in over 50 countries. The 5-year shelf life, rugged camouflage packaging (camouflaged foil for operational low-profile), gamma sterilization, and non-leachable removal make MIL-300-Z a strong choice for individual first line of defense (FLOD) trauma kits, special operations medical bags, and vehicle-based trauma kits.

How to Apply

1. Remove excess blood; identify and expose the bleeding source.
2. Open the Axiostat package and remove the Z-fold gauze.
3. Pack the wound tightly with the Axiostat gauze, feeding it to the bleeding source and filling the wound track.
4. Apply continuous pressure for at least 3 minutes until bleeding stops.
5. Do not remove or lift the gauze to check hemostasis — maintain pressure.
6. Use a secondary dressing over the Axiostat to secure it and prevent contamination.
7. At definitive care: irrigate with saline, gently remove. No residue remains.

Axiostat Z-Fold vs. QuikClot Combat Gauze

Both Axiostat MIL-300-Z and QuikClot Combat Gauze are wound-packing hemostatic gauzes of similar 3 in. × ~10 ft. length. The key distinction is mechanism: Combat Gauze (kaolin) activates Factor XII in the clotting cascade; Axiostat (chitosan/PBT®) acts independent of the cascade via muco-adhesion. QuikClot Combat Gauze remains the CoTCCC-recommended primary hemostatic for the U.S. DoD. Axiostat MIL-300-Z offers the cascade-independent advantage for coagulopathic, anticoagulated, or hypothermic patients, plus non-leachable clean removal. The Axiostat L88 patch is the complementary format for surface wound coverage.

Complete your hemorrhage control system with MED-TAC's hemostatic agents collection, massive hemorrhage control kits, and IFAK kits.

All products sourced from the actual brand manufacturer or authorized master distributors. CoTCCC recommendation status verified where applicable. Ships from MED-TAC International, Pembroke Pines, FL — clinician-founded, veteran-led, SDVOSB-certified.